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Tomlinson, Stephen
One or more keywords matched the following items that are connected to Tomlinson, Stephen
Item TypeName
Academic Article Targeting of functional antibody-decay-accelerating factor fusion proteins to a cell surface.
Academic Article Complement receptor 2-mediated targeting of complement inhibitors to sites of complement activation.
Academic Article Complement plays an important role in spinal cord injury and represents a therapeutic target for improving recovery following trauma.
Academic Article Highly specific inhibition of C1q globular-head binding to human IgG: a novel approach to control and regulate the classical complement pathway using an engineered single chain antibody variable fragment.
Academic Article A novel targeted inhibitor of the alternative pathway of complement and its therapeutic application in ischemia/reperfusion injury.
Academic Article A targeted inhibitor of the alternative complement pathway reduces angiogenesis in a mouse model of age-related macular degeneration.
Academic Article A complement-dependent balance between hepatic ischemia/reperfusion injury and liver regeneration in mice.
Academic Article Targeted inhibition of the complement alternative pathway with complement receptor 2 and factor H attenuates collagen antibody-induced arthritis in mice.
Academic Article Complement inhibition alleviates paraquat-induced acute lung injury.
Academic Article CD4+ T cells and complement independently mediate graft ischemia in the rejection of mouse orthotopic tracheal transplants.
Academic Article A targeted complement-dependent strategy to improve the outcome of mAb therapy, and characterization in a murine model of metastatic cancer.
Academic Article Targeted complement inhibition by C3d recognition ameliorates tissue injury without apparent increase in susceptibility to infection.
Academic Article Enhancement of antibody-dependent mechanisms of tumor cell lysis by a targeted activator of complement.
Academic Article Low-dose targeted complement inhibition protects against renal disease and other manifestations of autoimmune disease in MRL/lpr mice.
Academic Article Effects of active and inactive phospholipase D2 on signal transduction, adhesion, migration, invasion, and metastasis in EL4 lymphoma cells.
Academic Article A role for complement in the enhanced susceptibility of steatotic livers to ischemia and reperfusion injury.
Academic Article A new therapeutic strategy for lung tissue injury induced by influenza with CR2 targeting complement inhibitor.
Academic Article Targeted inhibition of complement activation prevents features of preeclampsia in mice.
Academic Article Targeted complement inhibitors protect against posttransplant cardiac ischemia and reperfusion injury and reveal an important role for the alternative pathway of complement activation.
Academic Article The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in MRL/lpr mice.
Academic Article A new treatment for neurogenic inflammation caused by EV71 with CR2-targeted complement inhibitor.
Academic Article Donor brain death exacerbates complement-dependent ischemia/reperfusion injury in transplanted hearts.
Concept Recombinant Fusion Proteins
Academic Article Targeted inhibition of complement using complement receptor 2-conjugated inhibitors attenuates EAE.
Academic Article Targeted mouse complement inhibitor CR2-Crry protects against the development of atherosclerosis in mice.
Academic Article A novel protocol allowing oral delivery of a protein complement inhibitor that subsequently targets to inflamed colon mucosa and ameliorates murine colitis.
Academic Article Complement-dependent modulation of antitumor immunity following radiation therapy.
Academic Article Dissecting the complement pathway in hepatic injury and regeneration with a novel protective strategy.
Academic Article A Targeted Inhibitor of the Alternative Complement Pathway Accelerates Recovery From Smoke-Induced Ocular Injury.
Academic Article Regulation of the alternative pathway of complement modulates injury and immunity in a chronic model of dextran sulphate sodium-induced colitis.
Academic Article Targeting pathogenic postischemic self-recognition by natural IgM to protect against posttransplantation cardiac reperfusion injury.
Academic Article Targeted Complement Inhibition Protects Vascularized Composite Allografts From Acute Graft Injury and Prolongs Graft Survival When Combined With Subtherapeutic Cyclosporine A Therapy.
Academic Article Identifying the Role of Complement in Triggering Neuroinflammation after Traumatic Brain Injury.
Academic Article Complement C3 activation regulates the production of tRNA-derived fragments Gly-tRFs and promotes alcohol-induced liver injury and steatosis.
Academic Article Complement C3-Targeted Gene Therapy Restricts Onset and Progression of Neurodegeneration in Chronic Mouse Glaucoma.
Academic Article C2 IgM Natural Antibody Enhances Inflammation and Its Use in the Recombinant Single Chain Antibody-Fused Complement Inhibitor C2-Crry to Target Therapeutics to Joints Attenuates Arthritis in Mice.
Academic Article Natural immunoglobulin M-based delivery of a complement alternative pathway inhibitor in mouse models of retinal degeneration.
Academic Article Chronic complement dysregulation drives neuroinflammation after traumatic brain injury: a transcriptomic study.
Academic Article In Situ Pre-Treatment of Vascularized Composite Allografts With a Targeted Complement Inhibitor Protects Against Brain Death and Ischemia Reperfusion Induced Injuries.
Academic Article Complement Inhibition Alleviates Cholestatic Liver Injury Through Mediating Macrophage Infiltration and Function in Mice.
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  • Recombinant Fusion Proteins